Biochemistry

Have a research assignment to do?

• Go to Understand Your Research Assignment to get some general tips to help you get started.

Have a different type of writing project to complete?

• Book report or exam essay: Occidental's Writing Center is the place to go.
• Literature review: How-to and examples
• Annotated Bibliography: How-to and examples
• How to write an abstract

Where to begin?

Read your assignment carefully and make sure you understand your Professor's instructions and expectations. Be sure to note any date or material type restrictions. (Example: Use only peer reviewed journals, locate articles from the past three years that explore.., etc.)

Next, follow your interest!  Brainstorm ideas about the topic of your assignment or research.  Try to make it something that sparks your curiosity or that you can relate to.  It will make your research more fun!

Then, think of some key words to describe your topic using both commonly used words as well as terms that may be used specifically in your subject (Example: in human anatomy, the word "eye" is commonly used but "ocular" and "ophthalmic" are other terms).

Now, it is time to do some reading and searching on your topic so move on to Finding Sources (below). 

Don't forget, if you get stuck at any point, you can always schedule an appointment with an Oxy librarian.

Finding sources (like articles and books) in databases is a lot like online shopping: you use a combination of keywords and filters to help you narrow down what you're looking for.  If you don't know much about your topic, start by looking for articles and books in Oxy OneSearch (our library catalog) or Google Scholar.  Once you have more knowledge about your topic, use the databases recommended in this Guide to access peer-reviewed or other scholarly material.  Navigate to the type of source you're looking for by using the menu on the left side of this guide.

What is PICO?

PICO is a mnemonic used to describe the four elements of a clinically oriented research question.

P= Population or Problem intended to study

I= Intervention or treatment plan intended to use

C= Comparison of one intervention to another (you may not always have this)

O= Outcome anticipated

Formulating a research question in the PICO format can help you build a list of helpful and relevant keywords to use when looking for sources.  Some examples of PICO questions and associated keywords can be found in this document about the PICO process.

These are the main types of information sources that you will encounter in your research:

• Manuscript/Research article: A formal research article that is submitted to the editor of a journal for publication, peer-review and/or to a preprint repository.  It reports the results of original research and assesses its contribution to the body of knowledge in a given area.  See "Format of Research Articles" below.  Considered a primary source article.
• Review article: An article that synthesizes and evaluates information from several primary articles.  It does not describe original research conducted by the author(s). Instead, it gives an overview of a specific subject by examining previously published studies on the topic. By interpreting the findings of previous studies, review articles are able to present the current knowledge and understanding of a specific topic.
• Peer-reviewed article: A manuscript or review article that has gone through an evaluation process in which independent expert scholars critically assess the quality and scientific merit of the article and its research.
• Preprint: An article that has not yet been peer-reviewed. Repositories like arXiv, bioRxiv and medRxiv house pre-print articles to allow for immediate access to research. It is the responsibility of the user of such preprints to vet the information in them and to regularly monitor the preprint repository to follow the status of the preprint.
• Case Report: Typically used in medical related fields.  It is a detailed report of the diagnosis, treatment, response to treatment, and follow-up after treatment of an individual patient or up to several patients.  It is used to describe a rare or unique condition or unexpected associations or findings.
• Conference Proceedings: In certain disciplines like Computer Science, Mathematics, and some sub disciplines of Cognitive Science, and Physics, conference proceedings are peer reviewed by conference committees and are considered equal to the process of peer review by a journal. This can be confusing since in other disciplines conference proceedings are not used or cited in scholarly wiring. When in doubt ask your professor for clarity.
• Dissertations and theses: Dissertations and theses are reviewed by committee members of the authors and while they are useful in research, most science scholars will recommend using the peer-reviewed papers published from these documents rather than citing the document itself. Again, there are disciplinary differences and when in doubt, reach out to your professor for clarity.
• Popular media/commercial websites: Online resources where individuals share their personal opinions and interpretations.  It is the responsibility of the reader/user to verify content before sharing it any further.

Discover advanced Research Strategies and information on Citation Management.